Injury surveillance is recommended by the WHO to inform injury prevention activities and the development of emergency care services. There is no routine hospital-based injury surveillance in the hospitals of Nepal. This study aims to evaluate the feasibility of a model of hospital-based injury surveillance. After receiving ethical approval from the Nepal Health Research Council and the University of the West of England (UWE Bristol, UK) training was given to eight data collectors and one supervisor between 16th - 22nd March 2019. The injury surveillance system started on 1st April 2019 in the emergency department of two hospitals in Makwanpur district; Hetauda Hospital and Chure Hill Hospital. Anonymous data on patients presenting with an injury will be collected 24 hours a day, 7 days a week for six-months initially, using an electronic data capture system (REDCap). Towards the end of the surveillance study we will interview data collectors and staff at the hospitals to explore the feasibility of continuing the surveillance beyond the initial six months and extending the model to other hospitals. We will study the data collected to better understand the epidemiology of injuries presenting to these hospitals, identify population groups at risk of different types of injuries and the risk factors associated with sustaining an injury. The implementation of this study has been undertaken with Mother and Infant Research Activities (MIRA).